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KMID : 0356919920250010072
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Korean Journal of Anesthesiology
1992 Volume.25 No. 1 p.72 ~ p.77
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The Effect of Venovenous Extracorporeal Lung Assist on the Arterial Oxygen Tension in Hypoxic Dogs
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Abstract
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Neonatal venoarterial(VA) extracorporeal lung assist(ECLA) drains venous blood from the right atrium via the right internal jugular vein and perfuses oxygenated blood to the aortic arch via the right common carotid artery. Though VAECLA supports
cardiac
function, it is not free from neurologic complications due to ligation of the carotid artery. Venovenous(VV)bypass is used early for acute respiratory failure. To reduce the number of veins ligated, a double lumen tube was developed. VV ECLA
using
the
double lumen tube was tried on eight hypoxic dogs at F1O2 0.15 Control values of hemodynamics and blood gases were obtained while the 0.8m2 kolobow lung ventilated with nitrogen gas. We measured the same parameters while ventilating the
oxygenator
with
oxygen(ECLA on). Mean arterial pressure and mean pulmonary arterial pressure were decreased significantly during ECLA on. Bypass flow rate was 1042(72ml/min and bypass ratio(bypass flow rate÷cardiac output (100) was 40(15%. Arterial oxygen
tension
wan
increased from 52(14 mmHg to 79(23 mmHg during ECLA on, whose saturation was 94(2%. Venous drainage was limited with a double lumen tube, but it can be used clinically for moderate hypoxemia with ease.
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